Optimal Adaptive Designs for Delayed Response Models: Exponential Case

نویسندگان

  • Janis Hardwick
  • Robert Oehmke
  • Quentin F. Stout
چکیده

We propose a delayed response model for a Bernoulli 2armed bandit. Patients arrive according to a Poisson process and their response times are exponential. We develop optimal solutions, and compare to previously suggested designs.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Adaptive Designs for Delayed Response Models

Adaptive designs are effective mechanisms for flexibly allocating experimental resources. In clinical trials particularly, such designs allow researchers to balance short and long term goals of improving patient well being. This tradeoff often takes the form of trying to minimize patient losses during the experiment while simultaneously gathering sufficient information to support decisions abou...

متن کامل

New Adaptive Designs for Delayed Response Models

Adaptive designs are effective mechanisms for flexibly allocating experimental resources. In clinical trials particularly, such designs allow researchers to balance short and long term goals. Unfortunately, fully sequential strategies require outcomes from all previous allocations prior to the next allocation. This can prolong an experiment unduly. As a result, we seek designs for models that s...

متن کامل

Friction Compensation for Dynamic and Static Models Using Nonlinear Adaptive Optimal Technique

Friction is a nonlinear phenomenon which has destructive effects on performance of control systems. To obviate these effects, friction compensation is an effectual solution. In this paper, an adaptive technique is proposed in order to eliminate limit cycles as one of the undesired behaviors due to presence of friction in control systems which happen frequently. The proposed approach works for n...

متن کامل

Optimal (Adaptive) Design and Estimation Performance in Pharmacometric Modelling

Maloney, A. 2012. Optimal (Adaptive) Design and Estimation Performance in Pharmacometric Modelling. Acta Universitatis Upsaliensis. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 166. 76 pp. Uppsala. ISBN 978-91-554-8491-0. The pharmaceutical industry now recognises the importance of the newly defined discipline of pharmacometrics. Pharmacometrics uses mat...

متن کامل

1 3 M ay 2 01 6 Bayesian D - optimal designs for error - in - variables models

Bayesian optimality criteria provide a robust design strategy to parameter misspecification. We develop an approximate design theory for Bayesian D-optimality for nonlinear regression models with covariates subject to measurement errors. Both maximum likelihood and least squares estimation are studied and explicit characterisations of the Bayesian D-optimal saturated designs for the Michaelis-M...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2000